Robert Sedlock, Director of Natoli Scientific
Abstract: In the past decade improvements have been made in the tablet compression industry. Compression tool designs are a critical aspect to the tableting process and this presentation will cover the impact of tablet quality with different cup configurations and specifications while utilizing USP<1062> Tablet Characterization Methods.
The tablet press system has also evolved over time and an explanation of the critical stages of the tablet press will be provided in this presentation. This includes proper die filling designs, uniform compression loading and how to properly scale from R&D to Manufacturing scale tableting. Case studies of USP<1062> compaction profiling of different drug loads for direct compression, roller compaction and wet granulation will also be presented.
Robert Sedlock is the Director of Natoli Scientific. He is a leading expert in the tablet compression industry with over 25 years of experience and authored numerous technical articles and journal publications. Robert’s earlier career spans in the design of instrumentation and data acquisition systems for the DOT, FAA and for pharmaceutical processing equipment. He is currently leading the Natoli Scientific team in the areas of pre-formulation, formulation development, formulation troubleshooting, and training seminars. Robert is also an adjunct faculty member at Long Island University, AMS School of Pharmacy in Brooklyn, NY.
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